Rodrigo Ruben, a member of the chair in BioMEMS and student of the Master of Science in Electronic Engineering desarrollael prototype of the pump. It is estimated that 170 million people worldwide suffer from diabetes , a disease that occurs when the pancreas stops insulin and glucagon, two hormones that control glucose levels in the blood. In an attempt to reverse this health problem , researchers at the Research Chair in BioMEMS have set a defiant challenge: to create an artificial pancreas that secrete same natural hormones from the pancreas. And to develop the first prototype, the department has divided the research into parts, so that each researcher to analyze one of the various components that comprise it, from the continuous glucose monitor (a device that measures glucose levels in the blood) to the adaptive control algorithm, which detects the ideal prototype will need each patient based on their metabolism.
Researchers at the Tecnológico de Monterrey , Campus Monterrey, developed an infusion pump that would provide insulin to the body of patients with diabetes and personalized automatically.
Rodrigo Ruben, a member of the chair in BioMEMS and student of the Master of Science in Electronic Engineering desarrollael prototype of the pump. It is estimated that 170 million people worldwide suffer from diabetes , a disease that occurs when the pancreas stops insulin and glucagon, two hormones that control glucose levels in the blood. In an attempt to reverse this health problem , researchers at the Research Chair in BioMEMS have set a defiant challenge: to create an artificial pancreas that secrete same natural hormones from the pancreas. And to develop the first prototype, the department has divided the research into parts, so that each researcher to analyze one of the various components that comprise it, from the continuous glucose monitor (a device that measures glucose levels in the blood) to the adaptive control algorithm, which detects the ideal prototype will need each patient based on their metabolism.
Insulin doser
One of the most important parts of the artificial pancreas is undoubtedly the infusion pump, as it will deliver insulin continuously, accurately and automatically without intervention by the patient or doctor. This part is developed by Rubén Rodrigo Lopez, a member of the department and a student of the Master of Science in Engineering (MSE) . "I'm developing an infusion pump, which is very accurate at the time of administering insulin and glucagon, both of which are necessary to maintain a stable level of blood glucose, but the amount must be exact, " said the student. He mentioned that there is a specific parameter, called the basal rate , over which supply conventional devices the supplements. However, he searches to find technology more accurate levels of insulin to be administered, which is around 0025 units per hour. "My master thesis is to use micro-level to improve the basal rate and power supply the drugs more precisely in terms of what the closed loop system can provide and what the doctors say. The idea is to make more effective therapies that the doctors or the same body requiring " he said. "This will prevent even the smallest increase in the basal rate, as the current pumps have a fairly large basal rate, and an excess in the supply of insulin causes the person to feel weak and suffers a mild hypoglycemia, ie low levels of blood glucose. By contrast, if the pump you choose another value, which is going to cause hyperglycemia " he said. He noted that the physical part of the infusion pump is made possible by the MEMS technology (microelectromechanical systems), specifically those made based plastics such as Parylene C, which are biocompatible, ie can be integrated into the human body and are chemically inert. "In fact we have already started with the development of this prototype. Micrometer measuring devices are about 430 micrometers. That is what is wanted, because MEMS systems have low power consumption and when a patient has a portable device is ideal to consume little power, that is portable, and is small, so that the person more independence " he said.
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